Humira starts tomorrow…

6 12 2012

I’m doing fine… I must have misunderstood Dr. B but I will not be on neupogen after all.  He said he doesn’t know why I couldn’t be on it with the IVIg/Humira, but he doesn’t want to play polypharmacy with me.  (I am still a big believer in throwing everything at the problem from the get-go, but I accept his choice… for now!)  So I start Humira on Friday– one shot, wait two weeks, another shot, wait three weeks, get my $450 Reprosource bloodwork done again and see if it worked.  If it didn’t, then another series of two shots/five weeks.  If it did, then IVIg by IV infusion, 14 days before transfer. 

As for side effects, the website says: Common side effects of HUMIRA include injection site reactions (redness, rash, swelling, itching, or bruising), upper respiratory infections (sinus infections), headaches, rash, and nausea.  Also,

  • Serious infections have happened in people taking HUMIRA. These serious infections include tuberculosis (TB) and infections caused by viruses, fungi, or bacteria that have spread throughout the body. Some people have died from these infections. Your doctor should test you for TB before starting HUMIRA, and check you closely for signs and symptoms of TB during treatment with HUMIRA. If your doctor feels you are at risk, you may be treated with medicine for TB.
  • Cancer. For children and adults taking TNF blockers, including HUMIRA, the chance of getting lymphoma or other cancers may increase. There have been cases of unusual cancers in children, teenagers, and young adults using TNF blockers. Some people have developed a rare type of cancer called hepatosplenic T-cell lymphoma. This type of cancer often results in death. If using TNF blockers including HUMIRA, your chance of getting two types of skin cancer (basal cell and squamous cell) may increase. These types are generally not life-threatening if treated; tell your doctor if you have a bump or open sore that doesn’t heal.
Sounds like fun, right?  Ahh, the things we’ll do to have children!
IVIg is supposed to make you feel like you have the flu while you get the infusion, and maybe for a day or two afterwards, but if you’re well hydrated you can avoid that to some extent.
I don’t know how long it will take to get me ready for a FET, I know there’s estrogen and other hormones I’ll be taking, and my linings weren’t the best the last two cycles (only like 7.3mm on trigger day, should be over 9) but Dr Braverman has a plan to improve the lining when we get there, so I’ll just flow with the go.  I have SUCH high TNF and IFN numbers (cytokines that indicate inflammation– stands for tumor necrosis factor-alpha and interferon-gamma) that I will not be surprised it takes more than one series of Humira.  In fact the last time we talked about it the doctor asked me if I would be willing to have a surrogate carry the baby!  (Uh, without any sisters, and without $60k to pay a surro, the answer was “no.”)  So I think he sees me as an uphill battle, too.
We go to Dallas this weekend, because my crown fell out while I was eating lunch on Tuesday and my brother in law is a dentist.  I had a local guy temporarily cement it back in place, but we’ll get a new one made (there was a small leak on one side, and though there’s no decay now, that’s not a good situation.)  My husband was going on a hunting trip with his college roommate this weekend, but DH is NOT a hunter, and wasn’t enthused about it especially with the warm weather we’ve been having.  Plus it’s a two-person deer blind, and his roomie is bringing his sons too… so sounded like my dental emergency was a blessing in disguise for DH.
Then the next weekend is our Christmas party/open house at our house… eggnog! champagne punch! lots of cookies I can’t eat!  And shortly thereafter we head for Virginia.  For the holidays, my husband and I alternate years with his family and mine.  This year, we’re going to Virginia to be with my side of the relations– we’ll spend 3 days in Washington DC for our own mini vacation, touring the museums especially the Smithsonian and staying in a friend’s condo while they’re away with their girlfriend… then 4 days with aunt/uncle/cousins in Norfolk, including Christmas dinner, then 4 days on the Eastern Shore of Virginia with people who are like second parents to me (they babysat me when I was in preschool with their sons, who are like brothers to me),  We’ll get back in Austin for New Year’s. 
How about you? 



4 responses

6 12 2012

Happy Holidays Georgette! I hope everything goes smoothly for you, I’m thinking of you. 🙂

18 12 2012

Stopping by from here in Austin to say hi! I hope you all have a wonderful Christmas and the Humira adjustment is going just fine.
I was wondering, what RE are you seeing in Austin? I’ve been seeing Dr. Silverberg at the Texas Fertility Center. He was firmly opposed to most immune testing.

24 12 2012

I’m an idiot – I realize you were referring to your out-of-town doc with the IgG. I thought for a minute you might’ve found someone here in town! Sorry!

26 12 2012

psh, no worries 🙂

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